Manatee Kayaking Company operates at Manatee Park in Fort Myers, FL, offering guided manatee eco-tours, kayak and canoe rentals, and a gift shop for paddling the Orange River to view manatees and wildlife, primarily mid-November through March.

Kayak Excursions offers year-round kayak and SUP rentals and guided tours in Fort Myers, Florida, since 2006. They provide fun, safe, and eco-friendly experiences for all skill levels, including eco tours, manatee tours, sunset tours, fishing tours, and flexible rentals with free delivery to locations like rental homes, hotels, and public launch sites in Lee County.

Royal Shell Port Sanibel Marina is a picturesque 'Old Florida' style marina in Fort Myers, Florida, at the mouth of the Caloosahatchee River, offering fishing charters, shelling charters, eco tours, sunset cruises, boat rentals, kayak rentals, and dry/wet boat storage with high-end amenities including a ship store and waterfront restaurant.

Offshore Hunter Charters offers top-rated deep sea and inshore fishing charters in Fort Myers, Sanibel, Captiva, and surrounding Southwest Florida areas. Guided by U.S. Coast Guard licensed captains Veiko and Chris Kreis, they provide customizable experiences including offshore trips for trophy fish like snapper and grouper, inshore fishing, wreck trips, and scenic shelling tours to Cayo Costa and North Captiva using a custom 36' Yellowfin center console boat.

Caloosahatchee Cowboy Charters is a family-owned fishing charter service based in Fort Myers, Florida, led by Captain Josh, a 4th generation local. It specializes in offshore and inshore fishing for trophy fish like tarpon, snook, redfish, and trout, while also offering sightseeing, dolphin tours, shelling, echo tours, combo cruises with lunch, sunset cruises, and guiding on private vessels.

FishSkinner Fishing Charters is an inshore and nearshore fishing charter and fishing guide service located in Fort Myers, Florida. They offer four, six, and eight hour fishing charters targeting Snook, Redfish, Trout, Shark, and Tarpon, as well as shelling excursions to Cayo Costa island.

Manatee Sightseeing & Wildlife Adventures offers the best wildlife tours in Southwest Florida, with a 97% success rate for seeing manatees in 2025. Family-friendly boat tours explore Port of the Islands Harbor and the Everglades, spotting manatees, alligators, dolphins, bull sharks, birds, and more on covered 6-passenger boats. Adventures include 1.5-hour Manatee Sightseeing tours, 3-hour Beach Eco-Tours with shelling, and Sunset Cruises to the 10,000 Islands.